Wireless small-scale medical robots have the unique capability of navigating, operating and staying inside hard-to-reach, tight, risky and deep sites inside our body. This talk reports our recent milli- and microscale wireless miniature medical robots down to cell size that could achieve various minimally invasive medical functions, such as targeted active drug delivery, neural stimulation, clot opening, liquid biopsy, biofluid pumping, cauterization, and hyperthermia. Due to miniaturization limitations on on-board actuation, powering, sensing, computing and communication, new materials and methods need to be introduced in creating and controlling such robots. Moreover, they need to be tracked under medical imaging modalities, such as ultrasound, fluoroscopy, photoacoustic imaging, and MRI, for their precise and safe operation. 3D microprinting and assembly-based fabrication methods and biocompatible and multifunctional soft composites with embedded micro/nanomaterials are proposed to create novel medical milli/microrobots. Soft-bodied medical miniature robot designs enable active shape programming-based adaptive, multimodal and multifunctional navigation and functions, and safe operation. External physical forces, such as magnetic fields, acoustic waves and light, and physical or chemical (e.g., catalytic) interactions with the operation medium are used to actuate and steer such miniature robots wirelessly as a single robot or robot collectives. These robots are aimed to save lives of more patients by curing diseases not possible or hard to cure and decrease the side effects and invasiveness of disease treatments drastically. 无线小型医疗机器人拥有独特的导航、操作能力，并能驻留在人体内难以触及、狭窄、危险和深处的部位。本次报告将介绍我们近期研发的毫米级至微米级（小至细胞尺寸）无线微型医疗机器人，它们能够实现多种微创医疗功能，例如靶向主动给药、神经刺激、血栓清除、液体活检、生物流体泵送、烧灼和高温治疗。 由于在机载驱动、供能、传感、计算和通信方面存在微型化限制，需要引入新材料和新方法来创建和控制此类机器人。此外，为了确保其操作的精确性和安全性，需要在超声、荧光透视、光声成像和磁共振成像（MRI）等医学成像模态下对它们进行跟踪定位。 我们提出采用三维微打印和基于组装的制造方法，以及嵌入微/纳米材料的生物相容性多功能软复合材料，来制造新型医疗毫米/微米机器人。软体医疗微型机器人设计能够实现基于主动形状编程的自适应、多模式和多功能的导航与操作，并确保安全运行。 利用外部物理力（如磁场、声波和光）以及与操作介质发生的物理或化学（例如催化）相互作用，可以无线驱动和引导此类微型机器人，无论是单个机器人还是机器人集群。这些机器人旨在通过治疗目前无法或难以治愈的疾病来挽救更多患者的生命，并大幅降低疾病治疗的副作用和侵入性。

Nature has evolved highly sophisticated machinery for organic synthesis, many of which resemble molecular assembly-line processes. So far chemists have been able to apply this type of approach in the synthesis of peptides, oligonucleotides and polysaccharides but it is much more difficult to apply iterative methodologies to organic synthesis.Here, we describe the application of iterative homologation of boronic esters using chiral lithiated carbamates and chloromethyllithium enabling us to grow carbon chains with control over both relative and absolute stereochemistry. Application of this strategy to the synthesis of the proposed structure of baulamycin and the real structure will be presented as well as other complex targets. 自然界已进化出高度精密的有机合成机制，其中许多类似分子装配流水线过程。迄今为止，化学家已能将这类方法应用于肽、寡核苷酸和多糖的合成，但将迭代方法应用于有机合成仍困难得多。我们在此阐述如何通过手性锂化氨基甲酸酯和氯甲基锂实现硼酸酯的迭代同系化反应，从而能够可控地构建碳链——包括相对与绝对立体化学的精准调控。该策略不仅将应用于bauromycin抗生素原定结构与真实结构的全合成验证，还将展示其在其他复杂目标分子合成中的应用。

生物制造作为生物技术与先进制造深度融合的颠覆性范式，已成为全球新一轮科技革命和产业变革的制高点。其通过重构物质生产底层逻辑，推动制造业向绿色化、智能化、可持续化跃迁，是培育新质生产力、重塑全球竞争格局的核心引擎。生物制造作为生物技术产业的重要组成部分，是生物基产品实现产业化的基础平台，也是合成生物学等基础科学创新在具体过程中的应用。未来生物制造相关技术将渗透到包括能源、材料、医药、食品、环境保护等多个行业的发展，对我国的传统产业的转型升级也将起到极为重要的作用。目前全球生物制造产业正处于技术攻坚和商业化应用开拓的关键阶段，发展先进生物制造技术，对于促进我国经济与环境协调与可持续发展、积极应对经济全球化与国际竞争，具有重大战略意义。本报告对全球生物制造产业发展现状、战略需求进行分析，围绕现阶段存在的问题，对未来生物制造发展的重点方向提出相关建议。

模空间，旨在参数化几何对象，在代数几何中具有核心地位。Mumford对负曲率曲线模空间的构造，构成了现代模空间理论发展的一个关键里程碑。对于高维代数簇，负曲率情形的模理论由Kollár等人系统发展，并与极小模型纲领形成了深刻关联。相比之下，正曲率情形，亦即Fano簇的模空间构造，则长期以来面临重大挑战，是高维几何中一个悬而未决的问题。近年来的重大进展表明，问题的核心在于对K-稳定性的深入理解。K-稳定性最初由田刚院士在复几何背景下提出，后经Donaldson的代数化重述，用以刻画Kähler-Einstein度量的存在性。本报告旨在梳理相关理论的发展脉络，阐释代数几何与复几何之间的相互作用，并重点讨论K-稳定性在Fano簇模空间构造中所发挥的核心作用。

Photovoltaic cells using molecular dyes, semiconductor quantum dots or perovskite pigments as light harvesters have emerged as credible contenders to conventional devices. Dye sensitized solar cells use a three-dimensional nanostructured junction for photovoltaic electricity production. They possess unique practical advantages in particular highly effective electricity production from ambient light, ease of manufacturing, flexibility and transparency, bifacial light harvesting, and aesthetic appeal, which have enabled industrial mass production and commercial applications. They served as a launch pad for perovskite solar cells which are presently being intensively investigated as one of the most promising future PV technologies, the power conversion efficiency of solution processed laboratory cells having currently reached 27 %. Present research focusses on ascertaining their long-term operational stability and scale up to pilot production of large modules. My lecture will cover our most recent findings in these revolutionary photovoltaic domains. 采用分子染料、半导体量子点或钙钛矿色素作为光捕获材料的光伏电池，已成为传统器件的强劲竞争者。染料敏化太阳能电池通过三维纳米结构结实现光电转换，具备独特的实用优势：包括弱光环境高效发电、易于制造、柔性与透明度俱佳、双面采光能力以及美学吸引力，这些特质促成了其工业化量产与商业应用。该技术更为钙钛矿太阳能电池的发展奠定基础——后者作为最具前景的未来光伏技术之一，其溶液加工实验室电池的功率转换效率目前已达27%，现阶段的重点研究在于确认其长期运行稳定性，并推进大型组件的试点量产。本次演讲将涵盖我们在这些革命性光伏领域的最新研究成果。

我们介绍费马提出的无穷下降法，探讨其在数论经典问题中的应用。无穷下降法通过构造矛盾性“无穷递减序列”，以反证形式否定解的存在性或揭示数的本质性质。费马运用这个方法给出了整数1不是同余数的证明；给出了佩尔方程解的递推结构。另外的例子还包括指数四的费马大定理和两平方和问题。